Answer :
The term that fits in the blank space given in the statement "_________ stimulates increased secretion of pancreatic juice that is rich in bicarbonate ions" is secretin.
Secretin is a peptide hormone secreted by the S cells of the duodenum and the jejunum in the small intestine. It is a type of hormone that promotes the secretion of bicarbonate-rich pancreatic juices into the small intestine. Secretin is formed by the S cells that are located in the crypts of Lieberkühn in the duodenum and jejunum of the small intestine.
In response to the acidic environment of the small intestine, secretion is activated. The acidic environment results from the mixing of stomach acid with food that has been recently consumed, and this mixture is known as chyme. Secretin signals the pancreatic ducts to secrete bicarbonate ions, which raise the pH of the small intestine, neutralizing the acidic chyme and allowing for proper digestion of nutrients. As a result, secretin plays an important role in the digestive process.
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