High School

Which of the following are caused by the release of cholecystokinin by duodenal enteroendocrine cells in response to protein- and fat-rich chyme?

Select all that apply:

A) Increased production of HCO₃⁻ by pancreatic duct cells
B) Increased secretion of pancreatic juice by acinar cells
C) Increased bile secretion by the liver
D) Suppression of gastric emptying
E) Relaxation of the hepatopancreatic sphincter
F) Gallbladder contraction

Answer :

The actions caused by the release of cholecystokinin (CCK) in response to high-protein and fat-rich chyme include increased secretion of pancreatic juice, increased bile secretion, suppression of gastric emptying, and gallbladder contraction, hence the correct answer is option B, C, D, F.

The release of cholecystokinin (CCK) by duodenal enteroendocrine cells in response to protein- and fat-rich chyme leads to several physiological responses:

  • B) Increased secretion of pancreatic juice by acinar cells - Cholecystokinin (CCK) stimulates the secretion of pancreatic enzymes by acinar cells to aid in the digestion of fats and proteins.
  • C) Increased bile secretion by liver - Cholecystokinin (CCK) stimulates the secretion of bile by the liver to aid in the emulsification and digestion of fats.
  • D) Suppression of gastric emptying - Cholecystokinin (CCK) does indeed slow down gastric emptying to allow for adequate digestion of fats and proteins.
  • F) Gall bladder contraction - Cholecystokinin (CCK) triggers the contraction of the gallbladder, leading to the release of stored bile into the duodenum.

Therefore the correct answer is B, C, D, F.