Answer :
Obstruction of pancreatic juice outflow by gallstones is the most likely cause of pancreatic tissue damage leading to acute pancreatitis, as it leads to the autodigestion of pancreatic cells.
The most likely cause of pancreatic tissue damage that leads to acute pancreatitis is the obstruction of pancreatic juice outflow by gallstones, leading to autodigestion of pancreatic cells.
When gallstones block the ducts through which pancreatic enzymes are released, these enzymes become trapped and begin to digest the pancreas itself. This process of autodigestion can cause inflammation and damage to the pancreatic tissues, resulting in acute pancreatitis.
Other causes include chronic alcohol use, certain infections, genetic factors, and certain medications. Treatment includes managing pain, and addressing the underlying causes, such as removing gallstones to restore the flow of pancreatic juices.