High School

Describe how the secretion of bile and pancreatic juice into the small intestine is regulated.

Answer :

Final answer:

  • Bile and pancreatic juice are released into the small intestine in response to hormonal signals. The hormone cholecystokinin triggers bile release when fats and proteins enter the small intestine.
  • Similarly, the arrival of acid stimulates secretin release which triggers the pancreas to release bicarbonate-rich fluid, and proteins and fats stimulate CCK release leading to pancreatic enzyme secretion.

Explanation:

The secretion of bile and pancreatic juice into the small intestine is strictly regulated by the body's hormonal and nervous systems. The gallbladder stores bile produced by the liver until it is needed during digestion. After you eat, the gallbladder contracts to release bile into the small intestine. This contraction is stimulated by the hormone cholecystokinin (CCK), which is released by the small intestine in response to the presence of fats and proteins.

The release of pancreatic juice is also regulated by the hormone CCK, and another hormone called secretin. When the acidic content of the stomach enters the small intestine, secretin is released. This stimulates the pancreas to secrete a bicarbonate-rich fluid that neutralizes the acid, allowing digestive enzymes to function optimally. The arrival of fat and protein in the small intestine triggers the release of CCK, which in turn causes the pancreas to secrete digestive enzymes into the small intestine to break down these nutrients.

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